Journal of Liver Cancer

Hyung Joon Kim

2 Articles

A Case of Mixed Hepatocellular and Cholangiocarcinoma: Jae Hyuk Do, Joong-Won Park, Hyung Joon Kim, Eon Seob Park, Jong Beom Lee, Byung Chul Yoo, Sill Moo Park; Journal of the Korean Liver Cancer Study Group. 2002;2(1):83-87. Published online July 31, 2002

Abstract PDF: Mixed hepatocellular and cholangiocarcinoma (HCC-CC) is an uncommon form of primary liver cancer. Definition of HCC-CC is both hepatocellular carcinoma and cholangiocarcinoma in the same tumor or in the same liver. We had experienced a case of HCC-CC. A 49 year-old male, who had social drinking history, admitted due to abdominal distension for about 4 days. Physical findings revealed that he had jaundice and ascites. The serum level of total bilirubin, direct bilirubin, AST, ALT, ALP and LDH were elevated. And serum levels of AFP and CEA were normal. But CA 19-9 level was elevated. Hepatitis B surface antibody was positive and anti-HCV antibody was negative. The level of SAAG was 1.4. The US and CT scans revealed heterogeneous echoic and hypodense multifocal mass like lesions were noted on the S6, S7, S8 and S5. And about 3 cm-sized hperechoic ovoid mass lesion was detected at S6. This lesions was not enhanced after contrast injection in CT scan. The IVC and hepatic veins were stenotic and right portal vein was obstructed due to thrombosis. But main portal vein, left portal vein and hepatic arteries were intact. We performed US　guide gun biopsy at this mass-like lesion in S6 and diagnosed as mixed hepatocellular and cholangiocarcinoma.

A Case of Hepatocellular Carcinoma: Curative Resection after Repeated Transcatheter Arterial Chemoembolization: Jae Hyuk Do, Joon Won Park, Hyung Joon Kim, Hyung Jin Shim, Byung Chul Yoo, Sung Il Park, Sil Moo Park; Journal of the Korean Liver Cancer Study Group. 2001;1(1):110-113. Published online June 30, 2001

Abstract PDF: A 57 year-old-male, who had a 40-year history of chronic alcohol dirnking, was referred to general weakness and jaundice for 1 month. Physical findings revealed that he had jaundice and spider angioma on anterior chest wall. The serum chemistries showed the total bilirubin 9.3 mg/dL and direct bilirubin level 6.1 mg/dL. The serum level of AST/ALT/AP was 130/192/494 IU/L. And the serum level of AFP was 18225.7 ng/ml. abdomen CT scan revealed the huge ill-defined hypodense mass was involving segment 2 and 3. The main portal vein and left portal vein were involved by this mass. Abdominal ultrasonography (US) showed huge echogenic mass in hilar portion of bile duct and tumor thrombosis in main and left portal vein. ERCP showed intraluminal-filling defect in CHD and complete obstruction of left IHD. We had a diagnosis this mass as hepatocellular carcinoma by US guided gun biopsy. Transcatheter arterial chemoembolization (TACE) was selected as the treatment due to TNM stage Ⅳa. After three times repeated TACE tumor decreased in size, regression of left portal vein invasion and normalization of jaundice, as a result, curative left lobectomy could be performed.